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Search Term: discovery & development tools


New Powerful Tool for Monitoring of Kinase Activity
Background:In the cellular signalling network, many enzymes and receptors are activated (phosphorylated) or deactivated (dephosphorylated) by protein kinases. As a result of these modifications, the function of the protein may change. Many disease processes including cancer, heart disease, diabetes, autoimmune and chronic inflammatory diseases are ...
Schizophrenia Animal Model
Background: Schizophrenia is a severely debilitating life-long disease with symptoms typically appearing in the early twenties, and consequently, it leaves a tremendous financial burden on patients and the society. Approximately 2.5 million Americans and 1% of the worldwide population (1 out of every 100 people) suffer from schizophrenia. The socia...
Cell Culture Supplements for Generating Mature, Functional, Stabilized Blood Vessels In Vitro
Background: The difficulty in generating complex functional blood vessels in vitro has been an important limitation to the adoption and application of complex cell based models for functional screening and drug discovery. While the formation of endothelial tubes is well known within the academic literature, the ability to generate integrated vessel...
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